Diagnosis & Testing
Advanced Prostate Cancer Diagnosis
When screening shows elevated PSA levels or something unusual on exam, getting an accurate diagnosis is the next step. Our diagnostic services use advanced imaging and expert analysis to give you clear answers about what’s going on.
Multiparametric MRI: A Clearer Picture
Multiparametric MRI has changed how we find and diagnose prostate cancer. This scan shows us suspicious areas before we do a biopsy, helps us understand where the cancer is and how far it’s spread, and lets us monitor men on active surveillance without needing repeated biopsies.
MRI helps us find cancers that actually matter while avoiding biopsies you don’t need. It shows us exactly where to look and gives us better information upfront. Radiologists who specialize in prostate imaging read every scan.
Getting the Right Biopsy
If you need a biopsy, we use MRI/ultrasound fusion technology. This combines the detailed view from MRI with real-time ultrasound, allowing us to target the exact spots that look concerning while also checking the rest of the prostate.
Fusion biopsy finds more significant cancers and fewer insignificant ones than older methods. It’s especially good at catching tumors in areas that standard biopsy often misses. If you’re thinking about active surveillance, this accuracy matters. We make sure you’re as comfortable as possible during the procedure.
What Your Biopsy Results Mean
Our pathologists analyze every tissue sample carefully. They use the Gleason grading system and Grade Groups to determine how aggressive your cancer is. Gleason 6 (Grade Group 1) is the lowest grade and grows slowly. Gleason 7 falls in the middle, with Grade Group 2 (3+4) and Grade Group 3 (4+3) having different levels of concern. Gleason 8 through 10 (Grade Groups 4 and 5) are the most aggressive.
We combine these grades with your PSA level and imaging results to determine the best path forward for you.
Genomic Testing for Better Answers
Sometimes we recommend genomic testing for extra information. If you have low-risk cancer and are considering active surveillance, tests like Oncotype DX Prostate can predict how aggressive it’s likely to be. After surgery, Decipher testing looks at your risk of the cancer spreading and helps us decide if you need additional treatment. For advanced disease, broader testing through Foundation One can identify specific mutations that may respond to targeted therapies.
Additional Imaging for Staging
Depending on your situation, we may recommend additional scans to see the full picture. This could include bone scans, CT scans of your abdomen and pelvis, a detailed pelvic MRI, or advanced PSMA PET scans if you have high-risk or returning cancer. We want complete information before we talk about treatment.
Your Complete Care Journey
Diagnosis is just one step in your comprehensive care at JHAH. Based on your results, our team will guide you seamlessly to the next phase of your journey.
Treatment Options Our Treatment Options provide personalized therapy plans using the latest advances in surgery, radiation, hormone therapy, and systemic treatments.
Prevention & Screening For those at increased risk, our Prevention & Screening programs offer individualized screening strategies and enhanced surveillance based on your risk profile.
Specialized Programs Our Specialized Programs bring together experts in prostate cancer to deliver personalized care for hereditary, advanced, and castration-resistant cases.
Support & Survivorship Throughout your journey, our Support & Survivorship Services ensure you have the emotional, practical, and educational resources you need.